For the first time since the U.S. and Israel launched a war on Iran, two American military planes have crashed in the region. Iran claims its military shot down an F-15 fighter jet and that another combat plane went down in the Persian Gulf. Vincent McAviney reports on the escalating risks of a drawn-out war. President Donald Trump has carried out a major purge of his administration and military leadership. Just hours after firing Attorney General Pam Bondi, Trump also dismissed the chief of staff of the U.S. army and two other generals. Jackson Proskow has the details. NASA’s historic Artemis II mission has blasted beyond Earth's orbit and is currently on its journey to the moon. The crew released new images of the entire planet, a view no human has seen in person for more than 50 years. Mike Armstrong is following the mission.  The House of Commons Standing Committee on Health has ordered the for-profit company Grifols and Canadian Blood Services to reveal the details of a confidential 15-year deal. Melissa Ridgen reports on the investigation. For more info, please go to https://globalnews.ca Subscribe to Global News Channel HERE: http://bit.ly/20fcXDc Follow Global News on X HERE: http://bit.ly/1Toz8mt Follow Global News on TikTok HERE: https://www.tiktok.com/@globalnews.ca?lang=en #globalnational