Shares of Salesforce jumped 22% Thursday after the company reported a beat on second-quarter earnings and announced an expanded partnership with artificial intelligence startup Anthropic.

The stock notched its second-best day ever, trailing only August 2020, when shares jumped roughly 26%.

CEO Marc Benioff and Anthropic CEO Dario Amodei joined CNBC to unveil the "Claudeforce" effort, which brings Salesforce into Claude with a plug-in built to help salespeople access critical data through the frontier lab's Claude chatbot.

The AI expansion fueled optimism and helped lift software names like Adobe, Palantir, ServiceNow, Autodesk and Figma, which all rallied. The iShares Expanded Tech-Software ETF climbed roughly 5%

Software stocks have taken a hit this year on fears that generative artificial intelligence could disrupt the software-as-a-service, or SaaS, business model.

"This is not the SaaSpocalypse," Benioff said on Wednesday's earnings call. "We've been hearing about this for last two quarters, these dire predictions about the end of software and how the models eat everything, but none of them have come true for us."

5-day stock chart of Salesforce (CRM).

Salesforce posted revenue of $11.35 billion, versus $11.32 billion that LSEG analysts expected. That was up 11% year over year. The software company reported adjusted earnings per share at $5.90, sailing past estimates of $3.27 a share.

Net income rose 87% from a year ago, coming in at $3.53 billion, or $4.29 a share, versus last year's $1.89 billion, or $1.96 a share.

The company also noted a $2.6 billion gain from its strategic investment in Anthropic, whose valuation has now grown to $965 billion ahead of its hotly-anticipated initial public offering.

Correction: This story has been revised to reflect that Salesforce's CEO is Marc Benioff. A previous version misspelled his name.