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Renewed collaboration builds on access provided to more than 300 patients with CLL to date and plans to support approximately 1,000 patients through 2028

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SAN CARLOS, Calif. & SEATTLE — BeOne Medicines Ltd. (“BeOne”) (Nasdaq: ONC; HKEX: 06160; SSE: 688235), a global oncology company, together with the BeOne Care Foundation, a nonprofit charitable foundation, and The Max Foundation, a leading global health nonprofit organization, today announced the renewal of their partnership through 2028 to expand access to BRUKINSA® (zanubrutinib) for the treatment of chronic lymphocytic leukemia (CLL) in low- and middle-income countries, with the program projected to support approximately 1,000 patients cumulatively.

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Building on a collaboration launched in 2023, the renewed partnership reflects the organizations’ shared commitment to improving access to innovative cancer treatments in underserved communities. To date, the partnership has enabled access to BRUKINSA for more than 300 patients with CLL across Armenia, Ethiopia, and Nepal, exceeding the program’s original scope by approximately 150 patients and helping establish access to innovative cancer care for patients who previously had limited or no treatment options.

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The collaboration combines The Max Foundation’s expertise in implementing oncology access programs with donated BRUKINSA from BeOne Medicines and a $1 million grant from the BeOne Care Foundation to support patient care, physician engagement, and operational infrastructure over the next two years.

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Pat Garcia-Gonzalez, Co-Founder and CEO, The Max Foundation, said:

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“We are thrilled to extend our collaboration with BeOne and the BeOne Care Foundation and further expand access to innovative treatment for people living with CLL in low- and middle-income countries. Working hand in hand with our partner physicians in Armenia, Ethiopia and Nepal we have been able to help hundreds of patients access treatment, enabling many of them to continue to support their families, spend time with loved ones and participate in their communities. We welcome BeOne Medicines and the BeOne Care Foundation’s shared commitment to expanding access to CLL treatment to more countries, patients and families, bringing dignity and hope to those in need.”

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John V. Oyler, Co-Founder, Chairman, and CEO, BeOne Medicines, said:

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“From the beginning, our goal has been to ensure that where a person lives does not determine whether they can access high-quality cancer care. Renewing this partnership with The Max Foundation reflects both the impact we have already achieved together and our commitment to reaching many more patients who otherwise may have limited treatment options.”

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Christine Riley Miller, President, BeOne Care Foundation, said:

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“The BeOne Care Foundation was established to help eliminate barriers to accessible cancer care in underserved communities. By investing in partners like The Max Foundation, we can help expand access to transformational medicines and strengthen the support systems patients need to achieve the best possible outcomes.”

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Renewal aims to expand access to new countries and support 1,000 patients through 2028

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Under the renewed agreement through 2028, the partnership will continue supporting patients in Armenia, Ethiopia, and Nepal, with potential expansion into additional countries, including Côte d’Ivoire, Malawi, Mongolia, Mozambique, Togo, and Zambia, based on operational readiness and evolving access priorities, bringing access through the program to patients in these countries for the first time.

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By 2028, the program is projected to support around 1,000 patients cumulatively, demonstrating the scalability of the partnership model and its potential to expand access to innovative cancer treatment globally. To support continuity of care, patients enrolled in the program will continue receiving treatment beyond the partnership term for as long as treatment is medically needed.

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CLL is the most common leukemia in adults, accounting for about one third of new cases of leukemia¹ and an estimated 191,000 new diagnoses² worldwide each year. Despite advances in treatment, patients in many low- and middle-income countries continue to face significant barriers to accessing innovative cancer therapies.

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About BeOne Medicines

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BeOne Medicines is a global oncology company that is discovering and developing innovative treatments for cancer patients worldwide. With a portfolio spanning hematology and solid tumors, BeOne is expediting development of its diverse pipeline of novel therapeutics through its internal capabilities and collaborations. The Company has a growing global team spanning six continents who are driven by scientific excellence and exceptional speed to reach more patients than ever before.